My very nervous 16 month old Dalmation/ Miniature Schnauzer mix Buddy does not like to be left alone without people or his big Lab sister. When Buddy would have to be alone, he would sometimes become destructive, anxious, whimper, and drool excessively. The first few times using this spray along with the CD, he was like a different dog. Much calmer and relaxed. I've tried lots of other products for him, but this is by far the best! We (and Buddy) are very happy with this product.